In the quest to boost absorption of curcumin, some experiments have been done using a combination of curcumin and black pepper (piperine).
One of the challenges using this combo is that piperine is contraindicated with many prescription medications because it negatively alters drug metabolism.
With the majority of the U.S. population taking some prescription drug, casual experimentation can have unintended consequences. A new study has shown piperine actually reduces the health benefits of curcumin.
Researchers have found the addition of piperine negatively impacted curcumin’s blood sugar balancing and reduction of oxidative stress. It also caused abnormal elevations in liver enzymes .
Further Reading: Herb-Drug Interactions: A Literature Review