Vitamin D Improves Heart Function

Nutrition News Vitamin D Issue: Good Day Sunshine!

A daily dose of vitamin D3 improves heart function in people with chronic heart failure,

a five-year University of Leeds research project has found.

Dr Klaus Witte, from the School of Medicine and Consultant Cardiologist at Leeds Teaching Hospitals NHS Trust, led the study, known as VINDICATE.

He said: “This is a significant breakthrough for patients. It is the first evidence that vitamin D3 can improve heart function of people with heart muscle weakness – known as heart failure. These findings could make a significant difference to the care of heart failure patients.”

Vitamin D3 can be boosted by exposure to sunlight, but heart failure patients are often deficient in it even during the summer because older people make less vitamin D3 in response to sunlight than younger people. Vitamin D3 production in the skin is also reduced by sunscreen.

The study, which was funded by the Medical Research Council, involved more than 160 patients from Leeds who were already being treated for their heart failure using proven treatments including beta-blockers, ACE-inhibitors and pacemakers.

Participants were asked to take vitamin D3 or a dummy (placebo) tablet for one year. Those patients who took vitamin D3 experienced an improvement in heart function which was not seen in those who took a placebo.

Changes in heart function were measured by cardiac ultrasound. Heart specialists measure heart function by taking an ultrasound scan of the heart (known as an echocardiogram) and measuring how much blood pumps from the heart with each heartbeat, known as ejection fraction.

The ejection fraction of a healthy person is usually between 60% and 70%. In heart failure patients, the ejection fraction is often significantly impaired – in the patients enrolled into the VINDICATE study the average ejection fraction was 26%.

In the 80 patients who took Vitamin D3, the heart’s pumping function improved from 26% to 34%. In the others, who took placebo, there was no change in cardiac function.

This means that for some heart disease patients, taking vitamin D3 regularly may lessen the need for them to be fitted with an implantable cardioverter defibrillator (ICD), a device which detects dangerous irregular heart rhythms and can shock the heart to restore a normal rhythm.

“ICDs are expensive and involve an operation” said Dr Witte. “If we can avoid an ICD implant in just a few patients, then that is a boost to patients and the NHS as a whole.”

One key aspect of this study is that the researchers avoided using a calcium-based supplement, as calcium can cause further problems for heart failure patients.

The findings from the VINDICATE study will be presented at the American College of Cardiology 65th Annual Scientific Session & Expo in Chicago on April 4.

Heart failure affects about 900,000 people in the UK and more than 23 million worldwide.

The condition can affect people of all ages, but it is more common in older people – more than half of all people globally with heart failure are over the age of 75.

Increase Your Bone Density With These Supplements

Steve just uploaded his latest podcast on how to build strong healthy bones for a lifetime. Thanks Steve.

“My wife increased her bone density by 7 % in 7 years.”

Steve LankfordI have worked with a lot of women regarding their bone health. It is one of the major concerns for women as they age. I know from personal experience as my wife went from osteopenia to osteoporosis by her mid 50s. This occurred even though she was on a quality bone support formula. She had the same result as thousands of other women who we desperate to stop the bone loss. Something was wrong.

The nutrients were all the reported required nutrients such as calcium, magnesium, zinc, copper, vitamins D, B6 etc. These were the better of the formulas available in the early 2000s. My wife was looking for a solution that did not involve the drugs.

It was at this time that we learned something new about osteoporosis. We learned that strontium is used as a treatment for osteoporosis in some parts of the world. We learned of another nutrient called ipriflavone which has a similar benefit, and we were all learning about the importance of higher dose vitamin D3. So these were added to her supplement program. Her doctor was skeptical and wanted her to take a bisphosphonate bone building drug. No, thank you. As a result, her bone density was increased by nearly 4 percent in 4 years. Wow. She was then 60 years old and building bone.

Around 2010 we began to learn more about bone support nutrients.We discovered BioSil (orthosilisic acid) a specific Building Healthy Bones for Lifeform of collagen building silica. And we learned about vitamin K2. And so these were added to her program. The result after 2 more years was another 3 percent improvement in bone density. She is up 7 % in 7 years. She is soon due for her next bone density scan. Will this trend continue? It’s been an exciting result so far, and we anticipate continued benefit.

This is an expensive program to follow if you take everything my wife takes. So here is my list in declining order of importance. I have no basis for this other than personal experience of my wife and other women I have advised. You need to determine the program that you are comfortable with and can afford.

  • A high quality natural bone support formula – if you aren’t sure visit a knowledgeable health food store. Print Bone Health Article PDFThere are now bone building formulas that include higher amounts of vitamin D3 and added K2. Some even include strontium as a separate formula. These may be the more cost effective but somewhat limited way to go. Look for quality brands and then compare formulas and price.
  • Vitamin D3 – Get tested and the adjust to the optimum dose for you.
  • Vitamin K2 – 80 to 100 mcg. per day.
  • BioSil – follow label directions.
  • Strontium – 680 mg. per day, taken apart from calcium.
  • ipriflavone – follow label directions.

In this podcast, I will give you my best advice for women who are concerned about osteoporosis. You can also print out a copy of my paper entitled “A Natural Approach to Bone Health”. You will find in depth interview on vitamin D3, K2 and BioSil at Search the TAG INDEX to easily find all related content.


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Suamico, WI 54173

Bulletproof Your Immune System This Winter

Discover the Simple, Affordable Solution

Your Doctor Won’t Tell You About

Thanks to Joshua Corn, Editor-in-Chief of the Live in the Now newsletter.

The time is right to be thinking about fortifying our immune systems as Winter approaches.The next issue of Nutrition News will be on Vitamin D. There’s new science about Vitamin D that you’ll want to know about.

In the meantime, enjoy Joshua’s article on Vitamin D. His timing couldn’t be better.

With winter fast approaching, you may be dreading the possibility of getting sick — the pain, discomfort and lost productivity can be truly dreadful.


And if you’re like me, you’re probably already thinking about ways to “bulletproof” your immune system so that you’ll stay healthy all winter long — even if everyone around you is coughing and sneezing.


But what you may not realize is that if you fail to do one simple thing, your efforts to avoid getting sick will largely be in vain!


Now, if you ask your doctor about how to avoid getting sick, the recommendation will surely be a shot. But please BEWARE that, in addition to side effects, even the CDC has admitted that the effectiveness rate of this “solution” is a mere 9%![1]


My advice to you: Don’t blindly follow the medical establishment’s recommendations. There are safe, effective and affordable measures you can take now to proactively ensure that your immune system stays healthy and strong all year long.


I’m Joshua Corn, Editor-in-Chief of Live in the Now, one of the fastest growing natural health publications in the nation. My passion for natural health has always driven me to educate people on alternative solutions that are both safe and effective.


Please keep reading, because I’m going to explain how one simple nutrient can help you avoid getting sick, and at the same time improve your mood, reduce aches and pains and keep your bones and heart healthy year-round.


Is This Widespread Deficiency to Blame
for Seasonal Sickness Outbreaks?


Now you won’t hear this from your doctor, but more and more experts agree that the single most effective way to avoid getting sick is by getting enough vitamin D. As you may be aware, vitamin D deficiency is now considered pandemic and worsens in the fall and winter months.


In fact, there is some evidence to suggest that widespread drops in vitamin D levels may be the long-overlooked trigger for seasonal sickness! A 2008 study published in the Journal of Virology led by Dr. John Cannell, MD, executive director of the non-profit Vitamin D Council, concluded that vitamin D may indeed have a “profound effect on prevention.”[2]


So vitamin D may be your key to staying healthy, especially in colder months, however don’t rush out of the house to grab any old bottle. It’s important you take the right kind and right amount to really get the full benefits…but more on that later.


Joshua Corn, Editor-in-Chief of the Live in the Now newsletter, is a health freedom advocate who’s been involved in the natural health movement for over 15 years. He’s always been dedicated to promoting health, vitality, longevity and natural living. Josh is currently writing a book on natural remedies and is gearing up to launch the Live in the Now radio show. In addition to his work in the natural health field, Josh is an avid outdoorsman, organic gardener, animal lover and enjoys “living in the now” with his wife and two sons.


Vitamin D Activates Your Full Immune Potential


Here’s a fact you need to know: Breakthrough research shows that vitamin D is critical to what is known as the innate immune system. This part of your immune system differs from the resistance you build when you’re exposed to a particular pathogen, known as acquired immunity.


Innate immunity is your body’s natural defense system, which protects your mucous membranes from pathogenic invaders. If your blood levels of vitamin D decrease rapidly, as often happens with lack of sun exposure during the winter months, your innate immunity suffers dramatically — sometimes catastrophically.


Researchers have also discovered that vitamin D triggers the killer cells of the immune system — called T cells — which fight off invaders. Without sufficient vitamin D in your bloodstream, your killer T cells will remain dormant, leaving the door wide open for pathogenic invaders to enter your body and wreak havoc.[3]


The Tell-Tale Signs of Vitamin D Deficiency

Please don’t fall into the trap of thinking you’re not vitamin D deficient. Way too many people have a “not me” attitude, but the truth is, a whopping 75% of adults in the U.S. have low vitamin D levels![4]


Vitamin D deficiency may be symptomless at first, but as it progresses it leads to weakened immunity and many health problems that may be easily misdiagnosed.


Aches and pains, cognitive problems, mood issues, fragile bones and heart trouble are just a few common symptoms of vitamin D deficiency.[5,6,7] What’s more troubling is that low vitamin D levels can ultimately result in premature death.[8,9,10] Sadly, many people are given drugs to “treat” a simple nutritional deficiency, or are just told to accept these health issues as part of aging. What a shame!


Signs of Vitamin D Deficiency
Weak immunity Cognitive problems
Aches and pains Vision loss
Low energy Fragile bones
Mood imbalances Heart problems


How to Protect Yourself with Vitamin D


There are only two ways to get vitamin D in the amounts you need for optimal immunity and overall health: several hours daily of direct sun exposure (without sunscreen, which blocks vitamin D production) and vitamin D supplementation.

So for most people, a vitamin D supplement is a must. You may eventually want to get your vitamin D levels tested by your doctor, but you shouldn’t wait to start. Vitamin D is one of the least toxic substances known on earth, making it nearly impossible to overdo it, and it doesn’t interact with most medications. The bottom line is that you’re better safe than sorry.

WARNING: Don’t Take Fake Vitamin D!


When doctors are paying attention to vitamin D levels, they often write a script for synthetic vitamin D2. Why? Because the pharmaceutical companies cannot patent natural compounds, so in order to make money, they had to create a synthetic version that’s poorly absorbed and less effective.


The better option is to take natural vitamin D3 (also known as cholecalciferol), which is what is used in most dietary supplements. It’s more absorbable, more affordable, more accessible and provides the greatest benefits, as proven by hundreds of scientific studies.[11]


How Much Vitamin D Do You Need?


Most people take way too little vitamin D per day, because the current RDA is only 600 IU. Many experts now agree that this is woefully inadequate. Sadly, the government has stubbornly refused to increase the RDA, putting millions at risk.


According to vitamin D expert Dr. John Cannell, healthy adults should supplement with 5,000 IU of vitamin D3 daily to avoid deficiency and achieve superior immunity and overall health — more than 8 times what the government says is sufficient! Remember, vitamin D has zero toxicity so there’s no harm in taking higher amounts.


Choosing the Right Vitamin D Supplement


I hope I’ve made the case as to why it’s critical to take supplemental vitamin D3. However, many people make the mistake of just taking whatever is on the shelf of their local drugstore. You need to know what to look for to avoid getting ripped off.


Here are my 3 tips to use as a buyer’s guide:


  1. The D3 form: Make sure you’re taking 100% natural vitamin D3 which is the safest, most absorbable and most effective form. Avoid synthetic vitamin D2.
  2. An optimal dose: Leading experts recommend 5,000 IU of D3 daily for optimal health. Most supplements provide far less than this.
  3. A rice bran oil base: Many supplements have a low quality soy oil base, that has toxins and GMOs. Instead look for a healthier rice bran oil base. Scientific References
    2. Virology. 2008 Feb; 5:9.
    3. University of Copenhagen. “Vitamin D crucial to activating immune defenses.” ScienceDaily, 8 Mar. 2010. Web. 1 Oct. 2013.
    4. Exp Biol Med. 2010 Sep; 235(9): 1034-45.
    5. Eur J Clin Nutr. 2010 Feb; 64 (2): 203-9.
    6. Curr Opin Clin Nutr Metab Care. 2009 Nov; 12 (6): 634-9.
    7. Clin Endocrinol (Oxf). 2009 Nov; 71 (5): 666-72.
    8. Curr Med Res Opin. 2008 Jan; 24 (1): 139-49.
    9. Endocrinol Metab Clin North Am. 2010 Jun; 39 (2): 401-18.
    10. Circulation. 2008 Jan 29; 117 (4): 503-11.
    11. Cochrane Database Syst Rev. 2011 Jul 6;(7):CD007470.






Vitamin D Nutritional Status Exhibits Long Half-Life In Body

Three-year follow-up of serum 25-hydroxyvitamin D,parathyroid hormone, and bone mineral density in nursing home residents who had received 12 months of daily bread fortification with 125 mug of vitamin D3

The need for vitamin D3 in the body is well established. What this study points out is that while vitamin d has a long lasting effect in the body when we get enough of it. When we don’t, it can lead to  serious issues including lower bone density.  At this stage, the corrective measures are vitamin d supplementation.

Veronica Mocanu and Reinhold ViethNutrition News Vitamin D

Abstract (provisional)


We conducted a single-arm clinical trial in institutionalized seniors, on the effects of high-dose vitamin D3-fortified bread daily intake ( registration NCT00789503).


At 1 and 3 years after the dietary fortification was stopped, serum 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH) and bone mineral density were measured in 23 of the original study subjects, aged 60-82 years who had consumed bread buns (100?g) fortified with 320?mg elemental calcium and 125??g (5,000?IU) vitamin D3 daily for one year.


At the end of the 1-year supplementation phase (receiving vitamin D3 fortified bread daily), mean (SD) serum 25(OH)D was 127.3???37.8?nmol/L (baseline for this follow-up).

  • At 1-year follow-up, the serum 25(OH)D was 64.9???24.8?nmol/L (p?=?0.001, vs. baseline); and
  • at 3-year follow-up it was 28.0???15.0?nmol/L (p?=?0.001 vs. baseline). Serum PTH was 18.8???15.6?pg/ml at baseline while
  • at Year 3 it was 48.4???18.4?pg/ml (p?=?0.001 vs. baseline). Lumbar spine BMD did not change from baseline to Year 3. However, by Year 3, hip BMD had decreased (0.927???0.130?g/cm2 vs. 0.907???0.121?g/cm2, p?=?0.024).


Vitamin D nutritional status exhibits a long half-life in the body, and a true steady-state plateau may not even be reached 1year after a discontinuation in dose.

Furthermore, once the need for vitamin D has been established, based on a low baseline serum 25(OH)D concentrations, the appropriate action is to maintain corrective vitamin D supplementation over the long term.

Trial registration Clinical trial registration number: NCT00789503

Vitamin D3 More Potent than Vitamin D2

Related Monographs: Vitamin D

Vitamin D is a fat-soluble vitamin that was isolated in 1930 and named calciferol. Since then more metabolites have been found, and the two major forms of this vitamin are now known to be vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Vitamin D is actually a hormone precursor, which can be manufactured by the body. Therefore, in a classical sense, it is not actually an essential nutrient. However, since the disease rickets is related to vitamin D deficiency, it has been traditionally classified as a vitamin.

Vitamin D is known as the “sunshine” vitamin. It is formed in the body by the action of the sun’s ultraviolet rays on the skin, converting the biological precursor 7-dehydroergosterol (found in animals and humans) into vitamin D3. Vitamin D3 is converted in the liver to 25-hydroxycholecalciferol (25-HCC) which is five times more active than vitamin D3. 25-HCC is then converted in the kidneys to 1,25-dihydroxycholecalciferol (1,25-HCC) which is 10 times more potent than vitamin D3. The active 1,25-HCC form of vitamin D is also called calcitrol. Since calcitrol is produced in the kidney and functions elsewhere in the body, it is considered a hormone, with the intestines and bone as its target.

A study published in the Journal of Clinical Endocrinology and Metabolism sought to determine whether vitamins D2 and D3 are biologically equivalent. The single-blind, randomized study included 33 healthy adults who were supplemented with 50,000 IU of either vitamin D2 or D3 per week for a total of 12 weeks.

The results revealed that after 12 weeks of supplementation, serum vitamin D levels increased significantly more in the D3 group than in the D2 group. The results were vitamin D3  was 56 to 87 percent more potent than D2 in raising serum vitamin D levels. It was also revealed that vitamin D3 produced a 2- to 3-fold increase in the storage of serum vitamin D, compared with vitamin D2. These findings suggest that vitamin D3 should be the preferred treatment for vitamin D deficiency due to its greater potency and lower cost.1

1 Heaney RP, Recker RR, Grote J, et al. Vitamin D3 Is More Potent Than Vitamin D2 in Humans. J Clin Endocrinol Metab. Dec2010.

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